After layers of screening and strict evaluation, Wuhan Feiyue Biotechnology Co., Ltd. has officially obtained the recognition as a “high-tech enterprise”. This signifies that the company has achieved significant achievements in technological innovation and research and development, injecting new momentum into the long-term development of the company. Since its establishment, Wuhan Biotechnology Co., Ltd. has…
Will endometrium increase nutrient supply? Mammalian embryos During natural conception, sperm and egg meet and combine in the fallopian tube to form a fertilized egg, but at that point, the woman isn’t actually pregnant, and there’s the crucial next step, implantation. This is a process in the early development of mammalian embryos, that is, the…
IL-33 released by senescent cells promotes the progression of obesity-related liver cancer Non-alcoholic fatty liver disease (NAFLD) Background Non-alcoholic fatty liver disease (NAFLD) has become an increasingly serious epidemic in recent decades as people’s lifestyles have become unhealthy. Globally, one in four people has non-alcoholic fatty liver disease. A large number of patients diagnosed with…
Intercellular Adhesion Molecule-1 What’s Intercellular Adhesion Molecule-1? ICAM-1 (also known as Intercellular adhesion molecule-1) is a protein encoded by the human ICAM1 gene. ICAM-1 is a glycoprotein on the cell surface and belongs to the immunoglobulin superfamily. It is mainly expressed on endothelial cells, immune cells, and other cell types. Intercellular adhesion molecule-1 Main Functions…
Uncovering Matrix Metalloproteinase 3 (MMP-3): The Cell “Scavenger” in the Body What is Matrix metalloproteinase 3 (MMP-3)? Matrix metalloproteinase 3 (MMP-3) is an important enzyme present in cells of our body. It plays an important role in maintaining physical health and disease development.Matrix metalloproteinase 3 (MMP-3) belongs to the matrix metalloproteinase family. Matrix metalloproteinases are…
The Key to Balanced Physical and Mental Health: Cortisol COR What’s Cortisol (COR)? Cortisol (COR) is an important concept that often mentioned when we talk about physical and mental health. Cortisol is a hormone secreted by the adrenal glands that plays a vital regulatory role in our physical and mental state. Cortisol COR Mechanism of…
Thyroxine T4: The Energy Source of the Body What is Thyroxine T4? Thyroxine T4 is an important hormone in the human body, synthesized by thyroid gland cells and composed of tyrosine and iodine atoms. T4 is a precursor hormone that can be converted into the more active triiodothyronine T3 when needed, which is directly involved…
ELISA sample preparation guide Sample preparation methods Cell culture supernatant Cell extract Conditioned medium Milk Plasma Urine Saliva Serum Tissue extract Volumes of lysis buffer must be determined in relation to the amount of tissue present. Typical concentration of final protein extract is >1 mg/mL. Cell/tissue extraction buffer recipe Additional reagents required to produce complete extraction buffer. Supplement…
B-cell activating factor (BAFF) What is BAFF? BAFF is a member of the tumor necrosis factor (TNF) family, involved in stimulating the function of B and T cells, and is an important factor for the survival and maturation of peripheral B cells. History of BAFF BAFF was first discovered in 1999 as a cytokine mainly…
Interleukin introduction Interleukins (ILs) are a group of cytokines (secreted proteins and signal molecules) that were first seen to be expressed by white blood cells (leukocytes). ILs can be divided into four major groups based on distinguishing structural features. However, their amino acid sequence similarity is rather weak (typically 15–25% identity). The human genome encodes…