IGG ELISA Kit

IgG (Immunoglobulin G) is the most common type of antibody, representing approximately 75% of serum antibodies in humans. IgG molecules are generated and released by plasma B cells, each IgG antibody has two different paratopes.

IgG ELISA kit Mechanism

The IgG is normal in blood and extracellular fluids, it can protect against bacterial and viral infections. The common mechanism of IgG are as following:

  1. IgG can bind and neutralize toxin.
  2. IgG is associated with type II and type III hypersensitivity reactions.
  3. IgG-mediated binding of pathogens can result in immobilization and binding together by agglutination. The IgG coating of pathogen surface promote phagocytic immune cells to recognize and ingest pathogen, in order to eliminate the pathogen.
  4. IgG activates the classical pathway of complement systems, this cascade of immune protein production will give rise to pathogen elimination.
  5. IgG has critical role in antibody-dependent cell-mediated cytotoxicity (ADCC) and intracellular antibody-mediated proteolysis. It can bind to TRIM21 and mark virions directly to the proteasome in the cytosol.

IGG ELISA kit is designed to detect immunoglobulin G (IgG), IgG has two identical antigen-binding sites with two light chains and two heavy chains. The main function of IgG is mediation of humoral immunity, protection against microbial pathogens. IgG ELISA kits are applied in research of the immune response against various infections. IgG has 4 different subclasses: IgG 1, IgG 2, IgG 3, IgG 4.

Human igg elisa kit

Human IgG ELISA Kit is designed for quantitative measurement of IgG protein in human serum, plasma, urine, saliva. Tissue extracts and culture media. Immunoglobulin G (IgG) belongs to immunoglobulin family, it consists of gamma (γ) heavy chain in the constant region. IgG is a widely expressed serum antibody, it has monomeric structure of two identical heavy chains and two identical light chains with MW of 50kDa and 25kDa respectively. The primary structure of this antibody has disulfide bonds inside the chians between the two heavy chains, the heavy and light chains.

IgG is subdivided into four classes of IgG1, IgG2, IgG3, and IgG4 with different heavy chains, and named γ1, γ2, γ3, andγ4, respectively.

Mouse igg elisa kit

Mouse IgG ELISA kit is a vitro enzyme-linked immunosorbent assay for quantitative measurement of IgG in mice, without cross reactivity versus bovine, horse and human IgG.

Rat igg elisa kit

Rat IgG ELISA kit is highly sensitive for the quantitative determination of IgG in rat biological samples, like:serum, plasma, hybridoma cell supernatants, ascites or other biological fluids.

Bovine igg elisa kit

Bovine IgG ELISA kit is an in-vitro assay for the quantitative measurement of bovine IgG in serum, plasma, cell culture supernatant and urine.

iGG elisa kit catalog